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dc.contributor.authorSilva, Beatriz Enóla Ribeiro da-
dc.date.available2021-12-28-
dc.date.available2022-01-04T20:39:42Z-
dc.date.issued2019-11-13-
dc.identifier.citationSILVA, Beatriz Enóla Ribeiro da. Efeito das mudanças climáticas sobre o metabolismo energético, antioxidante e neurológico do tambaqui (cuvier, 1818). 2019. 56 f. TCC (Graduação em Ciências Biológicas) - Universidade do Estado do Amazonas, Manaus.pt_BR
dc.identifier.urihttp://repositorioinstitucional.uea.edu.br//handle/riuea/3604-
dc.description.abstractClimate change has become one of the most discussed issues worldwide. According to the Intergovernmental Panel on Climate Change (IPCC) (IPCC, 2014), an increase of up to 6 ° C in the atmosphere is predicted for the year 2100. These changes directly affect the Amazonian aquatic environment and its organisms. These include changes in pH, temperature and oxygen, as well as causing damage to organisms by imposing behavioral, biochemical and morphological adjustments. Among these organisms is tambaqui (Colossoma macropomum), a species of high commercial value for the region and that has several adaptations to face periods of variations in temperature and seasonality of oxygen. Thus, the objective of this work was to evaluate how the effect of climatic scenarios and exposure to hypoxia affect the energy, antioxidant and neurological metabolism of individuals of the species. For this, the animals were acclimated for 30 days in scenarios RCP2.6 and RCP8.5 (4.5 ° C and 900 ppm CO2) (N = 42) and subsequently subjected to hypoxia for 6 hours (n = 7), After that, blood samples were collected for hematological analysis and tissues such as liver, brain, muscle and heart for enzymatic analysis and damage. The oxygen consumption variables show us that the species tries to maintain its consumption performance when kept in the extreme scenario in normoxia and hypoxia. For blood parameters, hemoglobin concentration ([Hb]), mean corpuscular hemoglobin (HCM) and mean corpuscular hemoglobin (CHCM) concentration were high (p <0.001), indicating that animals increase circulating hemoglobin to try to better supply tissue oxygen demand. Being observed the elevation of glucose concentrations when hypoxic for both scenarios (p <0.001) that is used by alternative pathways. The catalase (CAT) and glutathione-S-transferase (GST) enzymatic analyzes show us that the species does not present significant responses to the extreme scenario or lipoperoxidation damage. The same is expressed for LDH kinetics for the extreme scenario, and AChE remained almost unchanged for both scenarios, with a difference only in the current hypoxia (p <0.014). Thus, extreme scenarios and hypoxic conditions may condition metabolic stress in the animal interfering with the necessary adjustments. Keywords: Thermal adaptation; tambaqui; hypoxia; oxidative stresspt_BR
dc.languageporpt_BR
dc.publisherUniversidade do Estado do Amazonaspt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectAdaptação térmicapt_BR
dc.subjectTambaquipt_BR
dc.subjectHipóxiapt_BR
dc.subjectEstresse oxidativopt_BR
dc.subjectThermal adaptationpt_BR
dc.subjectHypoxiapt_BR
dc.subjectOxidative stresspt_BR
dc.titleEfeito das mudanças climáticas sobre o metabolismo energético, antioxidante e neurológico do tambaqui (cuvier, 1818)pt_BR
dc.title.alternativeEffect of climate change on the energetic, antioxidant and neurological metabolism of tambaqui (cuvier, 1818)pt_BR
dc.typeTrabalho de Conclusão de Cursopt_BR
dc.date.accessioned2022-01-04T20:39:42Z-
dc.contributor.advisor-co1Almeida e Val, Vera Maria Fonseca de-
dc.contributor.advisor-co1Latteshttp://lattes.cnpq.br/3821690425847852pt_BR
dc.contributor.advisor1Ferreira, Rosilene Gomes da Silva-
dc.contributor.advisor1Latteshttp://lattes.cnpq.br/3376667127204752pt_BR
dc.contributor.referee1Campos, Derek Felipe-
dc.contributor.referee1Latteshttp://lattes.cnpq.br/9932545658032162pt_BR
dc.contributor.referee2Mota, Susana Braz-
dc.contributor.referee2Latteshttp://lattes.cnpq.br/1619385871631270pt_BR
dc.creator.Latteshttp://lattes.cnpq.br/5721133938805957pt_BR
dc.description.resumoAs mudanças climáticas se tornaram um dos assuntos mais discutidos mundialmente. De acordo com o Painel Intergovernamental sobre Mudanças Climáticas (IPCC) (IPCC, 2014), está previsto um aumento de até 6 °C na atmosfera para o ano de 2100. Tais mudanças afetam diretamente o ambiente aquático amazônico e seus organismos, e se pode destacar dentre elas as alterações no pH, temperatura e oxigênio, além de acarretarem em danos aos organismos impondo ajustes comportamentais, bioquímicos e morfológicos. Entre esses organismos, está o tambaqui (Colossoma macropomum), uma espécie de alto valor comercial para a região e que possui diversas adaptações para enfrentar períodos de variações na temperatura e sazonalidade de oxigênio. Desta forma, o objetivo deste trabalho foi avaliar como o efeito dos cenários climáticos e exposição à hipóxia interferem no metabolismo energético, antioxidante e neurológico de indivíduos da espécie. Para isso, os animais foram aclimatados por 30 dias nos cenários RCP2.6 e RCP8.5 (4,5 °C e 900 ppm de CO2) (N=42) e submetidos subsequentemente à hipóxia por 6 horas (n=7); após isso, foram realizadas coletas de sangue para análises hematológicas, e tecidos como fígado, cérebro, músculo e coração para análises enzimáticas e danos. As variáveis do consumo de oxigênio nos mostram que a espécie tenta manter o desempenho de consumo quando mantidos no cenário extremo em normóxia e hipóxia. Para os parâmetros sanguíneos, a concentração de hemoglobina ([Hb]), hemoglobina corpuscular média (HCM) e concentração de hemoglobina corpuscular média (CHCM) foram elevadas (p<0,001), indicando que os animais aumentam a hemoglobina circulante para tentar suprir melhor a demanda de oxigênio tecidual. Foi observada a elevação das concentrações de glicose quando em hipóxia para os dois cenários (p<0,001), que é utilizada pelas vias alternativas. As análises enzimáticas catalase (CAT) e glutationa-S-transferase (GST) nos mostram que a espécie não apresenta respostas significativas para o cenário extremo nem para os danos em lipoperoxidação. Este é expresso para a cinética da LDH para o cenário extremo, e a AChE manteve-se quase inalterada para os dois cenários, havendo diferença somente no atual hipóxia (p< 0,014). Assim, os cenários extremos e condições de hipóxia podem condicionar estresse metabólico no animal interferindo nos ajustes necessários. Palavras-chaves: Adaptação térmica; tambaqui; hipóxia; estresse oxidativopt_BR
dc.publisher.countryBrasilpt_BR
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